Plants such as common bean, rice, soybean, tomato, and wheat exposed to different IR stimuli (e.g., picolinic acid, glutamate, phosphites, and a copper polyphenolic compound) developed a more robust antioxidant machinery that involved great APX, CAT, GR, and SOD activity levels to interfere with the infection by pathogens of different lifestyles [10,11,15,21,29]. The gene discussed is APEX1; the disease is infection.