Patients with CHD, overall and in subgroups, were selected with a similar age distribution and male prevalence and were well matched for serum lipid profile (total cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol, and non-HDL-cholesterol), apolipoprotein AI (apoAI) and apolipoprotein B (apoB) to minimize their confounding effect on the analysis. The gene discussed is APOB; the disease is coronary artery disorder.