Conversely, terms ATP binding (728 peptides, P < 0.005), metal ion binding (258 peptides, P < 0.005), structural constituent of ribosome (434 peptides, P < 0.005), and 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity/sorbitol-6-phosphate 2-dehydrogenase activity (2 peptides, P < 0.005) are negatively enriched both in T2D and in control patient groups. The gene discussed is DECR1; the disease is type 2 diabetes mellitus.