RNA-seq analysis showed that tumors in our cohort exhibited upregulation of numerous genes known to be highly overexpressed in ACC (e.g. PRAME, ELAVL2, SOX11, HAPLN1, VTCN1, GABRP, TTYH1, TLX1, ART3, EN1, BEX1, POU3F2 and FABP7) [65–71] including drivers associated with ACC carcinogenesis such as MYB, KIT, AXL, SOX4, CCND1, CCNB1 and CDK1 (Fig. 1A, Supplementary Table 3) [69, 72–74]. The gene discussed is GABRP; the disease is adrenal cortex carcinoma.