Apart from the well-known orthostatic hypotension, prior research has indicated a high prevalence of subclinical sinus node dysfunction (SND) [2] and sick sinus syndrome (SSS) [3] in LBD as well as a near ubiquitous involvement of the heart in the form of alpha-synuclein deposition in cardiac tissue [4, 5]. This evidence concerns the gene SNCA and sick sinus syndrome.