Combined with previous data suggesting a high prevalence of SSS [2, 3] and AF in LBD [21, 22], the presence of cardiac alpha-synuclein deposition in the hearts of the vast majority of LBD patients [4, 5], the results of this study suggest the presence of an LBD associated atrial cardiomyopathy that potentially could contribute to the challenging disease phenotype with cardiovascular complications and frequent falls. This evidence concerns the gene SNCA and atrial fibrillation.