PICALM and Alzheimer disease: In Fig. 3c–e, we show the cell-type-specific colocalization probabilities (PP.H4 > 0.8) for AD, highlighting several genes known to confer risk to AD such as BIN1 (PP.H4microglia = 1.0), RASGEF1C (PP.H4microglia = 1.0) and PICALM (PP.H4microglia = 1.0), as well as less well-established AD risk genes such as SNX31 (PP.H4astrocytes = 0.99), JAZF1 (PP.