The mean proportion of SBS30 in adenomas from biallelic NTHL1 cases was, however, significantly higher compared with the mean proportion in non-hereditary adenomas (74.5 %±9.4 % versus 2.8 %±1.3 %; p-value=5.1 × 10–7) (Fig. 2B andTable 3). Here, NTHL1 is linked to adenoma.