To investigate whether the rescue of depressive‐ and anxiety‐like behaviors in CUMS rats as achieved with overexpression of 204–5p involves downregulation of the JAK2‐STAT3 signaling pathway, we examined the protein levels of JAK2 and p‐STAT3 in CUMS rats with an overexpression of miR‐204‐5p (Figure 7A,B). The gene discussed is STAT3; the disease is Anxiety.