As a means to assess whether the JAK2/STAT3 signaling pathway may contribute to depressive‐ and anxiety‐like behaviors in miR‐204‐5p deficient rats, we injected SC99 or WP1066, the JAK2/STAT3 signaling pathway inhibitor, for 7 days after virus infection 2 weeks in miR‐204‐5p knockdown rats. This evidence concerns the gene JAK2 and Anxiety.