Liver cell apoptosis triggered by KP is dependent on the Bcl-2 family-mediated apoptosis pathway [61], and another study found that the addition of BC alleviated the hepatocyte apoptosis in rats by up-regulating Bcl-2 gene, and down-regulating Bax and Caspase-3 genes [62]. The gene discussed is CASP3; the disease is keratosis pilaris.