GH1 and susceptibility to pneumonia measurement: As shown in Table 2, the incidence of pneumonia, intracranial infections, bloodstream infections and urinary tract infections did not differ between GH group and nGH group (73.20%, 3.09%, 2.06%, 6.19% vs 74.82%, 4.32%, 2.88%, 7.19%, P = 0.779, 0.629, 0.695, 0.762, respectively).