While previous studies on other cancer types have highlighted the role of VASP interaction with FA adapter protein including vinculin, integrin superfamily and RIAM in promoting metastasis [23, 45, 54], our investigation did not reveal the co‐expression of VASP with these FA adapter proteins in the filopodia region of OSCC cell lines (Fig. 1E and Fig. S2). Here, VCL is linked to cancer.