Case 2 had an FCD, as did another patient harboring a KCNB1 variant in a previously reported case.[2] Pathogenic mutations in genes encoding ion channels have been shown to result in FCD.[11] Therefore, while FCD is rare in patients with KCNB1 variants, it is reasonable to assume that pathogenic variants in KCNB1 are associated with FCD. Here, KCNB1 is linked to fleck corneal dystrophy.