According to the expert consensus on GS published by the Kidney Disease Improving Global Prognosis Organization (KDIGO) in 2017, kidney stones and kidney cysts are usually considered unfavorable features for the diagnosis of GS.[2] However, Chen et al reported a case of a patient with GS confirmed by SLC12A3 gene testing, who presented with multiple bilateral kidney stones and cysts. This evidence concerns the gene SLC12A3 and medical procedure.