CXCR4 and autoimmune thrombocytopenic purpura: BM plasma CXCL12 concentrations in patients with ITP were not significantly different from those in HDs (Figure S11F, Supporting Information), suggesting that MIF may play a dominant role in the inflammatory response mediated by CXCR2/CXCR4/CD44/CD74/CXCR7.