Hepatitis viruses can induce immune responses through lectin‐dependent mechanisms, such as the interaction between hepatitis C virus (HCV)‐derived glycosylated envelope proteins E1 and E2 and MBL.[39] Helicobacter pylori (H. pylori) infection may play a role in the development of ITP.[40] Infection with H. pylori can affect the innate immune response in a lectin‐specific manner,[41] and virulent strains of H. pylori stain can express mannans.[42] Additionally, placenta and embryo‐derived exosomes may play a role in thrombocytopenia through dysfunctional immune tolerance during pregnancy. Here, ERVW-1 is linked to autoimmune thrombocytopenic purpura.