INS and fatty liver disease: In the previous studies, we demonstrated that exposure to BPA at a concentration of 50 μg kg−1 day−1 induced hepatic steatosis, IR, and impaired insulin secretion.[2a–c] Furthermore, perinatal exposure to this dose of BPA was associated with increased body weight and disrupted glucose and lipid homeostasis in adult offspring.[7a] To further investigate, contrast, and deepen our understanding of these effects, the present study employed this specific dosage.