Interestingly, an increased expression of ANKRD26 was also reported in a family whose thrombocytopenia was caused by a complex structural variant generating a WAC-ANKRD26 fusion transcript [9], suggesting that the loss of ANKRD26 downregulation is a common mechanism in Its, including ANKRD26-RT and FPD/AML. The gene discussed is ANKRD26; the disease is acute myeloid leukemia.