According to UC GRN analysis, VDR is capable of regulating the expression of TP53TG1 and SATB2-AS1 along with 409 CD common overregulated DEGs, which are known to be co-expressed in colon cancer, and related to transmembrane transporter activity, phosphorylation, mitochondrial and peroxisome function, PPAR, and multiple metabolic pathways and diseases. This evidence concerns the gene VDR and colonic neoplasm.