AEBP1 is the AE binding protein 1, a transcriptional regulator common in PAH and colon cancer that positively controls MAP-kinase activity, a key signaling pathway identified in the annotation analysis (Figure 5), leading to enhanced cell proliferation and reduced cell differentiation, inflammation, macrophage cholesterol homeostasis, and atherogenesis [155]. The gene discussed is AEBP1; the disease is pulmonary arterial hypertension.