SATB2-AS1 inhibits tumor metastasis, affects the tumor immune cell microenvironment in colorectal cancer by regulating SATB2 [99], and mediates epigenetic regulation of SATB2 and Snail expression to suppress colorectal cancer progression and aggressiveness by inhibiting SATB2-dependent snail transcription and epithelial–mesenchymal transition [100]. This evidence concerns the gene SNAI1 and colorectal cancer.