TSPAN7 has not been previously analyzed in gut and lung inflammatory diseases but promotes the migration and proliferation of lung cancer cells via epithelial-to-mesenchymal transition [46], regulates several types of cancer cell growth, metastasis, stemness, drug resistance, and biogenesis of extracellular vesicles (exosomes and migrasomes), and the immune-microenvironment [45]. The gene discussed is TSPAN7; the disease is lung cancer.