According to UC GRN analysis, VDR is capable of regulating the expression of TP53TG1 and SATB2-AS1 along with 409 CD common overregulated DEGs, which are known to be co-expressed in colon cancer, and related to transmembrane transporter activity, phosphorylation, mitochondrial and peroxisome function, PPAR, and multiple metabolic pathways and diseases. Here, VDR is linked to malignant colon neoplasm.