METTL3 and cancer: Moreover, the long non-coding RNA (lncRNA) Arf GTPase Activating Protein 2 Antisense RNA 1(AGAP2-AS1) enhances the assembly of the WTAP/METTL3/METTL14 m6A methyltransferase complex, stabilizing Signal Transducer and Activator of Transcription 3(STAT3) mRNA and activating the Interleukin 6(IL6)/STAT3 signaling pathway, which promotes cancer cell proliferation and migration [83].