Our comprehensive analysis identified that four compounds emblicanin A, punigluconin, penta-o-galloylglucose and quercetin can target eight proteins (BCL2, BCL2L1, c-Met, HSP70, EGFR, FGFR1, PTGS2 and TNFα) involved in multiple cellular processes and elucidating mechanism such as pathways, including cancer, PI3K-Akt, EGFR and MAPK signaling pathways associated with growth factors and receptors. Here, PTGS2 is linked to cancer.