CD80 and melanoma: In addition, it has been found that Honey-Roasted Astragalus Polysaccharide (HP-APS), obtained by mixing astragalus with honey, not only effectively inhibits the growth of melanoma cells in vitro, thereby playing a role in melanoma resistance, but also significantly enhances the expression of HSP70, CRT, MHC-1, CD86, CD80, and ATP release in vivo.