Although targeting other proteins that play roles in centrosome clustering (Rhys and Godinho, 2017; Sabat-Pospiech et al, 2019) can induce multipolar spindles and reduce cancer cell growth, such as Hsp72, Nek6 (Sampson et al, 2017) or STAT3 (Morris et al, 2017), no therapeutic approaches have yet reached clinical trials. The gene discussed is STAT3; the disease is cancer.