Additionally, BNT111, a liposomal RNA vaccine, targets four non-mutated tumor-associated antigens, including New York esophageal squamous cell carcinoma 1 (NY-ESO-1), tyrosinase, MAGE family member A3 (MAGE-A3), and transmembrane phosphatase with tensin homology (TPTE), in melanoma. This evidence concerns the gene MAGEA3 and melanoma.