For example, a pan-cancer TCGA analysis found that tumor overexpression of SLC39A3, SLC39A5, and SLC39A11 was associated with better overall survival after bladder cancer diagnosis, whereas tumor overexpression of SLC39A2, SLC39A8, SLC39A9, and SLC39A14 was associated with poorer survival30. This evidence concerns the gene SLC39A8 and urinary bladder cancer.