For example, the Chicago Health and Aging Project revealed that adherence to a healthy lifestyle was related to a slower rate of cognitive decline in both APOE ε4 carriers (β = 0.029, 95% CI, 0.013–0.045) and noncarriers (β = 0.013, 95% CI, 0.005–0.022)16, with similar findings observed across different ancestry groups in the following study15. The gene discussed is APOE; the disease is Mental deterioration.