To address whether reprogramming of the myeloid compartment by PI3Kγ contributes to tumour control, we employed the previously described KPC-F cell line derived from an LSL-KrasG12D/+;Trp53R172H/+;Pdx1-Cre C57BL/6 tumour to generate orthoptic tumours13 (figure 1G). The gene discussed is PDX1; the disease is neoplasm.