HGF and breast carcinoma: umbrosushas a potent cytotoxic effect against breast cancer cell line (MCF-7) with an IC50value of 20 μg/mL.10The cytotoxicity of cisplatin was tested as a positive control and it was found to possess strong cytotoxicity against both HSC-3 and HGF cell lines with an IC50value of < 20 μg/mL, which suggests that cisplatin does not employ a selective inhibitory effect.