ING5 and diffuse large B-cell lymphoma: Consistent with our findings, loss of ING5 has been recently reported to reduce hematopoietic stem cell numbers [25] and single cell sequencing studies of lymphomas have implicated epigenetic regulation of immune recognition molecules in the genesis of germinal centre DLBCL [46], the form of lymphoma we see is induced by loss of the ING5 epigenetic regulator.