Lipoprotein-associated phospholipase A2 (Lp-PLA2) is located at 6p21.2 comprises on 12 exons an enzyme involved in both lipoprotein metabolism and inflammatory pathways produced such compounds that are responsible in progression of atherogenesis, making it a potential therapeutic target for coronary heart disease (CHD) [21]. This evidence concerns the gene PLA2G7 and coronary artery disorder.