APC and prostate neoplasm: In a panel of three genes, methylation of GSTP1, APC, and MDR1 in prostate tumors was significantly associated with pathological stage (p < 0.001), Gleason score (p < 0.001), capsular involvement (p < 0.001), vesicle invasion (p = 0.002), and pelvic lymph node metastasis (p = 0.001) [43].