For example, VIM binds to the 5′‐UTR stem‐loop domain of collagen mRNAs, regulating collagen synthesis, and interacts with the 3′ UTR of certain mRNAs, such as alkaline phosphatase mRNA in human primary osteoblasts and tissue factor mRNA in human breast cancer cells, stabilizing them and thus influencing their expression levels.24 This evidence concerns the gene VIM and breast carcinoma.