Figure 3 demonstrates the absence of significant differences in the values of these parameters between patients with BC who tested positive for ER and PR. Multiple studies have established a correlation between BC triggered by estrogen and the presence of oxidative stress [22]. Furthermore, oxidative DNA damage has been reported to be highly correlated with the presence of ER and is higher in BC issues than in normal breast tissues [23, 24]. Here, ESR1 is linked to breast cancer.