YAP1 and Familial prostate cancer: Regarding the correlation between Hippo-YAP signaling and prostate cancer stem cell (PCSC) characteristics, Nong et al.13 discovered that reduced death-associated protein kinase 1 expression might promote stem cell-like traits in PCa cells through activating zinc finger E-box-binding homeobox-1 via the Hippo/YAP signaling pathway.