TEAD1 and acute kidney injury: Therefore, we crossed TEAD1flox/flox (TEAD1CON) mice with PEPCKCre+/- mice to generate proximal-tubule-specific TEAD1 knockout mice (TEAD1PKO) and examined the role of proximal tubule TEAD1 in the pathogenesis of AKI induced by cisplatin administration (Supplementary Figure S1A).