As of interest, DLAT expression was also positively correlated with CX3CL1 (r = 0.331, P <0.001), TLR4 (r = 0.551, P < 0.001) and HMGB1 (r = 0.448, P <0.001), but negatively correlated with TNFRSP18 (r = -0.461, P <0.001) in patients with ccRCC (Fig. S3I-L). This evidence concerns the gene CX3CL1 and nonpapillary renal cell carcinoma.