For the diagnostic value of cuproptosis differential genes in ccRCC patients, the AUCs of FDX1, DLD, DLAT, PDHA1, GLS, PDHB and CDKN2A were 0.965, 0.909, 0.813, 0.939, 0.956, 0.849 and 0.991, respectively (Fig. 3H). The gene discussed is PDHB; the disease is nonpapillary renal cell carcinoma.