PDHA1 and nonpapillary renal cell carcinoma: For the diagnostic value of cuproptosis differential genes in ccRCC patients, the AUCs of FDX1, DLD, DLAT, PDHA1, GLS, PDHB and CDKN2A were 0.965, 0.909, 0.813, 0.939, 0.956, 0.849 and 0.991, respectively (Fig. 3H).