IGF1 and posterior cortical atrophy: The results of RE-IVW analysis found that IGF-1 (OR = 1.14, 95% CI: 1.06-1.23; p<0.001) and LPA (OR = 1.12, 95% CI: 1.01-1.25; p=0.038) were associated with increased risk of PCa (Figure 3).