Univariate Cox survival analysis showed significant prognostic value for KLRD1 in several cancers, acting as a protective factor in adrenocortical carcinoma (ACC), cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), HNSC, low-grade glioma (LGG), and skin cutaneous melanoma (SKCM) (Figure 1C). This evidence concerns the gene KLRD1 and adrenal cortex carcinoma.