Western blotting revealed that the expression of the biomarkers of EMT, N-Cadherin, Vimentin, and Snail was downregulated or upregulated after SLC5A1 knockdown or overexpression, which further demonstrated that SLC5A1 could regulate colon cancer cell migration and invasion (Figure 2L). The gene discussed is CDH2; the disease is malignant colon neoplasm.