TP53 and gastric cancer: According to the study by Hwang et al.34 on endometrial and ovarian cancer 28, the level of p53 expression was divided into three groups: Strong expression (>10% of tumor cells had strong positivity), expression deficiency (tumor cells did not have nuclear staining) and weak expression (weak positivity, scattered or patchy positivity).In this study, the simple yin and yang dichotomy of p53 was discarded, and the triple classification method of many scholars 28-31,34,35 was adopted to classify p53 staining in the tissues of patients after radical gastric cancer surgery.