Similarly, with each unit increase in serum prostate-specific antigen levels, chance of occurrence of benign prostatic hyperplasia (OR: 1.70; 95% CI; p<0.001) and prostate cancer (OR: 2.13; 95% CI; p<0.001) increases by 70% and 113%, respectively considering all other parameters to be constant. The gene discussed is KLK3; the disease is Familial prostate cancer.