There was no significant correlation between the plasma levels of MMP1, MMP7, MMP10, and MMP12 and an increased risk of IDD (IVW: p = 0.39; p = 0.46; p = 0.87; p = 0.72) (Table 2) Please refer to the Supporting Information for details. The gene discussed is MMP10; the disease is intervertebral disk degenerative disorder.