It has been demonstrated that the levels of AT1-AA are significantly higher in patients with LN than in those with other primary glomerulopathies, such as membranous glomerulonephritis, IgAN, and FSGS (38), although no significant differences have been detected in comparison with patients with cytoplasmic or perinuclear antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. The gene discussed is AGTR1; the disease is focal segmental glomerulosclerosis.