It has been demonstrated that the levels of AT1-AA are significantly higher in patients with LN than in those with other primary glomerulopathies, such as membranous glomerulonephritis, IgAN, and FSGS (38), although no significant differences have been detected in comparison with patients with cytoplasmic or perinuclear antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. This evidence concerns the gene AGTR1 and lobular neoplasia.