SMARCA4 and Friedreich ataxia: BRG1 and Fanconi anaemia complementation group D2 (FANCD2) are mutually interdependent on R‐loop, and BRG1 collaborates with the Fanconi anaemia (FA) pathway to resolve transcription‐replication (T‐R) conflicts to prevent R‐loop accumulation and related DNA damage, thereby addressing genomic instability [73].