A recent GWAS representing the largest association study for dementia identified ANKH, GRN, PLEKHA1, SNX1 and UNC5CL as new genes of interest,40 which validates our analysis here, because we also identify these genes as putative risk genes for AD, with a much smaller sample size than in the new AD GWAS. The gene discussed is PLEKHA1; the disease is Alzheimer disease.