In young mice, pulmonary bacterial burden, PMN infiltration, FITC‐dextran lung permeability, and bacteremia were unchanged by the addition of Siv to CDDO treatment (Figure 6a,d–f, “Young”: “Sp + CDDO + Siv.” vs. “Sp + CDDO”), suggesting that CDDO and Siv preserve AJCs in a redundant fashion in young hosts. Here, TFF2 is linked to bacterial infectious disease with sepsis.