However, we found 10 variants of uncertain significance (VUS) in clinically relevant CPG (groups 1–3) in 5 KTR and 3 donors (one KTR and one donor carried VUS in two genes, Table 3), including 1×VUS in the SDHB gene encoding the succinate dehydrogenase (SDH) complex subunit associated with kidney cancer risk. This evidence concerns the gene SDHB and kidney cancer.