CA = contact allergy; DKG = German Contact Dermatitis Research Group (Deutsche Kontaktallergie-Gruppe); MI = methylisothiazolinone; MCI = methylchloroisothiazolinone; ACE = angiotensin converting enzyme; BARS = Biologics Asthma Response Score; ACT = asthma control test; FEV1 = forced expiratory volume in 1 second; CyA = cyclosporin A. This evidence concerns the gene ACE and contact dermatitis.