In preliminary studies, we also have identified a series of GDM genetic polymorphisms in the Guilin population, such as the OR2D2 gene rs1965211, RXR-γ rs2134095, TSNARE1 rs7814359, XAB2 rs3760675, ERBB4 rs1595066, MTNR1B rs10830963, CDKAL1 (rs7756992 and rs7754840), and ACE2 (rs6632677 and rs2074192) (16–21). The gene discussed is CDKAL1; the disease is gestational diabetes.