We found that the C-3G-B-3E, C-3D-B-3E, B-3G-C-3E, and B-3D-C-3E bispecific TRuC-T cells prepared by the combination of either CD3γ-CD3ε or CD3δ-CD3ε had high expression levels of TRuCs on T cells that could efficiently kill multiple myeloma cells. Here, CD3E is linked to plasma cell myeloma.