The western blotting analysis also confirmed that, although there were no rules to follow for Bax expression, cleaved caspase-3 expression was significantly downregulated and BCL2 expression was increased in hDPSCs-treated mice as compared with that in AD+PBS mice (Figure S18C, D), which was further identified by immunofluorescent staining of cleaved caspase-3 (Figure S18B). The gene discussed is BAX; the disease is Alzheimer disease.