The results of another bilateral common carotid artery ligation (2-VO) model of VD corroborated the significance of Aβ in VD, revealing that the same dose of GAS was efficacious in mitigating neuronal damage in VD rats by inhibiting Aβ production, lowering Aβ1-40/42 levels and activating tubulin associated unit (tau). The gene discussed is MAPT; the disease is sexually transmitted disease.